Documentaries

Aerodyne Nimbus 195: A racing drone so tough you can drive your car over it

Aerodyne Nimbus 195 is about as rugged as we've ever seen for an FPV racer

 

 
Aerodyne Nimbus 195 is about as rugged as we’ve ever seen for an FPV racer(Credit: Aerodyne)

A drone you can drive your car over? Thanks to a spherical, carbon fiber monocoque exoskeleton, this FPV racing drone can take one hell of a beating – or a dunk in the snow or a puddle – and could save the average pilot a fair bit of tinkering time after a crash.

FPV drone flying is a ton of fun, but crashing is a big part of the sport, and while we’re generally pretty impressed with the way ready-to-fly kit racers like the Walkera F210 take a pounding, they do have a lot of exposed electronics that eventually get bashed and wrecked in our incapable hands.

That’s why the Aerodyne Nimbus 195 looks like such a great idea. Instead of being built on a multi-layered flat, straight carbon frame like most racers, the Nimbus has its innards built into and totally protected by a carbon monocoque exoskeleton, formed from the inside in a cavity mold and with thickness varying from 1 to 4 millimeters depending on the stresses each area needs to take.

 

Aerodyne Nimbus 195: cutaway showing electronic internals

 

This sphere-based shape is tough enough to go under the wheels of a car without cracking, and its stubby arms are just as tough, taking high speed brick wall impacts with ease – at least in the promo video. There’s also bound to be some aerodynamic benefits for hard chargers.

Keeping the gizzards inside the shell lets the Nimbus achieve an IP54 water ingress protection rating, which effectively means splash protection in case you stack it into the snow or a puddle.

 

Aerodyne Nimbus 195: happy to take a dunk in the snow since its internals are protected

 

Of course, this kind of frame construction is labour intensive and thus not cheap; a frame by itself is listed at an early bird rate of US$160 in Aerodyne’s Nimbus Indiegogo campaign, and a bind and fly package, giving you a fully functional racing drone with good quality components and no controller, will run you some $490. For the ready to fly package including controller you are looking at a $750 outlay, with deliveries slated for March 2017.

Still, if it’s as strong as it looks, it should solidly outlast a regular frame, not to mention saving you all those little bits of time and fiddling and money when components break. And if it keeps you in the air longer, who’s to say that’s not money well spent?

See the Nimbus take an absolute pounding in this video:

 

Source: Aerodyne RC

January 18, 2017 / by / in , , , , , , , , ,
Newly-discovered protein keeps your biological clock running

Scientists have discovered a new protein that regulates cellular agingScientists have discovered a new protein that regulates cellular aging(Credit: AnatomyInsider/Depositphotos)

 

 

We’re all familiar with the inescapable effects that the march of time has on our bodies, but the processes that drive aging are still offering up surprises. Scientists have long known that DNA segments called telomeres play a crucial part in our aging process, but new research has discovered a protein that acts as a kind of cellular timekeeper, regulating the length of telomeres to maintain healthy cell division and prevent the development of cancer.

Each time a cell divides, a tiny section of DNA is lost, and while this could be devastating to the cell, our bodies have a natural defense against the loss of any important genetic information. Telomeres are little caps made of repetitive sections of DNA at the end of each chromosome, and whenever a cell divides they take the hit. The problem is, telomeres have a set length, and as they degrade over time that buffer zone eventually stops protecting the important bits of information, leading to the well-known bodily wear-and-tear we associate with aging.

“Telomeres represent the clock of a cell,” says Eros Lazzerini Denchi, corresponding author of the study. “You are born with telomeres of a certain length, and every time a cell divides, it loses a little bit of the telomere. Once the telomere is too short, the cell cannot divide anymore.”

 

Telomeres are short, repeating sections of DNA at the ends of chromosomes, which help protect important...

 

Logically then, longer telomeres should lead to longer lives, right? Technically yes, and that’s an area that scientists have been experimenting with for years. Back in 2010, a Harvard study was able to slow and even reverse the aging process in mice by manipulating telomerase, an enzyme that helps replenish telomeres. Breakthroughs on the road to applying the process to human cells followed, with the discovery that telomerase can function like an “off” switch, and a new procedure to extend the life of lab-grown cells.

But it’s not as simple as just lengthening telomeres and enjoying a similarly-lengthened life. If cells are allowed to divide unchecked, that same freedom also applies to cancerous cells, increasing the risk of tumors developing.

“This cellular clock needs to be finely tuned to allow sufficient cell divisions to develop differentiated tissues and maintain renewable tissues in our body and, at the same time, to limit the proliferation of cancerous cells,” says Lazzerini Denchi.

 

 

Associate Professor Eros Lazzerini Denchi (left) and Gracrditduate Student Julia Su Zhou Li led the study...Associate Professor Eros Lazzerini Denchi (left) and Gracrditduate Student Julia Su Zhou Li led the study at The Scripps Research Institute (Credit: Madeline McCurry-Schmidt)

 

Until recently, scientists thought they knew of all proteins that bind to telomeres: namely telomerase and Shelterin, a protein complex that helps protect telomeres and regulate telomerase. But now scientists from the Scripps Research Institute have discovered a new protein, called TZAP.

TZAP’s role is to control a process called telomere trimming, which keeps the telomeres within that sweet spot of proliferation: long enough to be healthy, but below the risky upper limit. While the discovery may not have a direct application to increasing overall human lifespan yet, improving our understanding of these crucial processes can help pave the way for these kinds of advances in future.

“This study opens up a lot of new and exciting questions,” says Lazzerini Denchi.

The research was published in the journal, Science.

Source: The Scripps Research Institute

January 18, 2017 / by / in , , , , , , , ,
ReRAM can now store and process data in the same chip

Researchers in Singapore and Germany have developed a chip that can not only process data, like...

Researchers in Singapore and Germany have developed a chip that can not only process data, like the one above, but can also act as memory storage(Credit: Mark800/Depositphotos)

 

Those lucky enough to work from home will probably tell you that one of the best things about it is the time saved by not commuting to the office. Inside a computer, data goes through a similar process, commuting between its “home” in the system memory to “work” in the processor, but now researchers in Singapore and Germany have found a way to help that data effectively work from home. The team is developing memory chips that can process information right where it’s stored, potentially allowing for faster, smaller and more efficient computers and mobile devices.

The new circuit is based on Resistive switching RAM (ReRAM) memory chips, which are just starting to become commercially available. These chips store information by effectively remembering a variable value of electrical resistance, which can be changed by applying different currents, and being non-volatile, they can retain that memory even while turned off. Also known as a “memristors,” these chips are said to function like the neurons in a human brain, and are sought after due to the fact that they’re faster, smaller, can store more data and require less energy to run.

Memristors have been projected to be the future of both memory and processors, and the new circuit combines them both into one device. Developed by scientists at Nanyang Technological University in Singapore, RWTH Aachen University, and the Forschungszentrum Juelich research center, the ReRAM chip could remove the need for separate processing and memory components, leading to smaller and thinner devices that use less power. And since there’s no wait time for data to run between the storage and processor, they will be faster too.

“ReRAM is a versatile non-volatile memory concept,” says Professor Rainer Waser, co-author of the study. “These devices are energy-efficient, fast, and they can be scaled to very small dimensions. Using them not only for data storage but also for computation could open a completely new route towards an effective use of energy in the information technology.”

The binary system, where information is represented with a series of ones and zeroes, is standard practice, but the team says translating data into this digital language takes time and can slow the process down.

“This is like having a long conversation with someone through a tiny translator, which is a time-consuming and effort-intensive process,” says Anupam Chattopadhyay, co-author of the study. “We are now able to increase the capacity of the translator, so it can process data more efficiently.”

To do so, the team is making use of ReRAM’s ability to store data in an analog format – that is, it can register on a more detailed gradient scale, rather than the simple on or off of binary. The prototype circuit uses what’s called the Ternary number system, which can store and process data using three states: zero, one or two. While it’s not truly analog yet, it’s a step in that direction.

The next step for the researchers is to develop a system that allows ReRAM to process and store data with higher amounts of states, as well as reaching out to companies to help develop commercial products that make use of the findings.

The research was published in the journal Scientific Reports.

January 18, 2017 / by / in , , , , , , ,
The Technological Future of Surgery

The future of surgery offers an amazing cooperation between humans and technology, which could elevate the level of precision and efficiency of surgeries so high we have never seen before.

 

Will we have Matrix-like small surgical robots? Will they pull in and out organs from patients’ bodies?

The scene is not impossible. It looks like we have come a long way from ancient Egypt, where doctors performed invasive surgeries as far back as 3,500 years ago. Only two years ago, Nasa teamed up with American medical company Virtual Incision to develop a robot that can be placed inside a patient’s body and then controlled remotely by a surgeon.

That’s the reason why I strongly believe surgeons have to reconsider their stance towards technology and the future of their profession.

 

Virtual Incision - Robot - Future of Surgery

 

Surgeons have to rethink their profession

Surgeons are at the top of the medical food chain. At least that’s the impression the general audience gets from popular medical drama series and their own experiences. No surprise there. Surgeons bear huge responsibilities: they might cause irreparable damages and medical miracles with one incision on the patient’s body. No wonder that with the rise of digital technologies, the Operating Rooms and surgeons are inundated with new devices aiming at making the least cuts possible.

We need to deal with these new surgical technologies in order to make everyone understood that they extend the capabilities of surgeons instead of replacing them.

Surgeons also tend to alienate themselves from patients. The human touch is not necessarily the quintessence of their work. However, as technological solutions find their way into their practice taking over part of their repetitive tasks, I would advise them to rethink their stance. Treating patients with empathy before and after surgery would ensure their services are irreplaceable also in the age of robotics and artificial intelligence.

As a first step, though, the society of surgeons has to familiarize with the current state of technology affecting the OR and their job. I talked about these future technologies with Dr. Rafael Grossmann, a Venezuelan surgeon who was part of the team performing the first live operation using medical VR and he was also the first doctor ever to use Google Glass live in surgery.

 

Future of Surgery

 

So, I collected the technologies that will have a huge impact on the future of surgery.

1) Virtual reality

For the first time in the history of medicine, in April 2016 Shafi Ahmed cancer surgeon performed an operation using a virtual reality camera at the Royal London hospital. It is a mind-blowingly huge step for surgery. Everyone could participate in the operation in real time through the Medical Realities website and the VR in OR app. No matter whether a promising medical student from Cape Town, an interested journalist from Seattle or a worried relative, everyone could follow through two 360 degree cameras how the surgeon removed a cancerous tissue from the bowel of the patient.

This opens new horizons for medical education as well as for the training of surgeons. VR could elevate the teaching and learning experience in medicine to a whole new level. Today, only a few students can peek over the shoulder of the surgeon during an operation. This way, it is challenging to learn the tricks of the trade. By using VR, surgeons can stream operations globally and allow medical students to actually be there in the OR using their VR goggles. The team of The Body VR is creating educational VR content as well as simulations aiding the process of traditional medical education for radiologists, surgeons, and physicians. I believe there will be more initiatives like that very soon!

 

 

2) Augmented reality

As there is a lot of confusion around VR and AR, let me make it clear: AR differs in two very important features from VR. The users of AR do not lose touch with reality, while AR puts information into eyesight as fast as possible. With these distinctive features, it has a huge potential in helping surgeons become more efficient at surgeries. Whether they are conducting a minimally invasive procedure or locating a tumor in liver, AR healthcare apps can help save lives and treat patients seamlessly.

As it could be expected, the AR market is buzzing. More and more players emerge in the field. Promising start-up, Atheer develops the Android-compatible wearable and complementary AiR cloud-based application to boost productivity, collaboration and output. The Medsights Tech company developed a software to test the feasibility of using augmented reality to create accurate 3-dimensional reconstructions of tumors. The complex image reconstructing technology basically empowers surgeons with X-ray views – without any radiation exposure, in real time. The True 3D medical visualization system of EchoPixel allows doctors to interact with patient-specific organs and tissue in an open 3D space. It enables doctors to immediately identify, evaluate, and dissect clinically significant structures.

 

Google Glass - Future of Surgery

 

Grossmann also told me that HoloAnatomy, which is using HoloLens to display real data-anatomical models, is a wonderful and rather intuitive use of AR having obvious advantages over traditional methods.

 

3) Surgical robotics

Surgical robots are the prodigies of surgery. According to market analysis, the industry is about to boom. By 2020, surgical robotics sales are expected to almost double to $6.4 billion.

The most commonly known surgical robot is the da Vinci Surgical System; and believe it or not, it was introduced already 15 years ago! It features a magnified 3D high-definition vision system and tiny wristed instruments that bend and rotate far greater than the human hand. With the da Vinci Surgical System, surgeons operate through just a few small incisions. The surgeon is 100% in control of the robotic system at all times; and he or she is able to carry out more precise operations than previously thought possible.

Recently, Google has announced that it started working with the pharma giant Johnson&Johnson in creating a new surgical robot system. I’m excited to see the outcome of the cooperation soon. They are not the only competitors, though. With their AXSIS robot, Cambridge Consultants aim to overcome the limitations of the da Vinci, such as its large size and inability to work with highly detailed and fragile tissues. Their robot rather relies on flexible components and tiny, worm-like arms. The developers believe it can be used later in ophthalmology, e.g. in cataract surgery.

 

Da-Vinci-Surgical-Robot - Future of Surgery

 

4) Minimally Invasive Surgery

Throughout the history of surgery, the ultimate goal of medical professionals was to peak into the workings of the human body and to improve it with as small incisions and excisions as possible. By the end of the 18th century, after Edison produced his lightbulb, a Glasgow physician built a tiny bulb into a tube to be able to look around inside the body.

But it wasn’t until the second half of the 20th century when fiber-optic threads brought brighter light into the caverns of the body. And later, tiny computer chip cameras started sending images back out. At last, doctors could not only clearly see inside a person’s body without making a long incision, but could use tiny tools to perform surgery inside. One of the techniques revolutionizing surgery was the introduction of laparoscopes.

The medical device start-up, Levita aims to refine such procedures with its Magnetic Surgical System. It is an innovative technological platform utilizing magnetic retraction designed to grasp and retract the gallbladder during a laparoscopic surgery.

The FlexDex company introduced a new control mechanism for minimally invasive tools. It transmits movement from the wrist of the surgeon to the joint of the instrument entirely mechanically and it costs significantly less than surgical robots.

 

 

5) 3D Printing and simulations in pre-operative planning and education

Complicated and risky surgeries lasting hours need a lot of careful planning. Existing technologies such as 3D printing or various simulation techniques help a lot in reforming medical practice and learning methods as well as modelling and planning successfully complex surgical procedures.

In March 2016 in China, a team of experienced doctors decided to build a full-sized model of the heart of a small baby born with a heart defect. Their aim was to pre-plan an extremely complicated surgery on the tiny heart. This was the first time someone used this method in China. The team of medical professionals successfully completed the surgery. The little boy survived with little to no lasting ill-effects.

In December 2016, in the United Arab Emirates doctors have used 3D printing technology for the first time to help safely remove a cancerous tumour from a 42-year-old woman’s kidney. With the help of the personalized, 3D printed aid the team was able to carefully plan the operation as well as to reduce the procedure by an entire hour!

The technology started to get a foothold also in medical education. To provide surgeons and students with an alternative to a living human being to work on, a pair of physicians at the University of Rochester Medical Center (URMC) have developed a way to use 3D printing to create artificial organs. They look, feel, and even bleed like the real thing. Truly amazing!

 

 

To widen the platform of available methods for effectively learning the tricks of the trade, Touch Surgery developed a simulation system. It is basically an app for practicing procedures ranging from heart surgery to carpal tunnel operations.

 

6) Live diagnostics

The intelligent surgical knife (iKnife) was developed by Zoltan Takats of Imperial College London. It works by using an old technology where an electrical current heats tissue to make incisions with minimal blood loss. With the iKnife, a mass spectrometer analyzes the vaporized smoke to detect the chemicals in the biological sample. This means it can identify whether the tissue is malignant real-time.

The technology is especially useful in detecting cancer in its early stages and thus shifting cancer treatment towards prevention.

 

Surgical iKnife - Future of Surgery

 

7) Artificial Intelligence will team up with surgical robotics

Catherine Mohr, vice president of strategy at Intuitive Surgical and expert in the field of surgical robotics believes surgery will take to the next level with the combination of surgical robotics and artificial intelligence. She is thrilled to see IBM Watson, Google Deepmind’s Alpha Go or machine learning algorithms to have a role in surgical procedures. She envisioned a tight partnership between humans and machines, with one making up for the weaknesses of the other.

In my view, AI such as the deep learning system, Enlitic, will soon be able to diagnose diseases and abnormalities. It will also give surgeons guidance over their – sometimes extremely – difficult surgical decisions.

Artificial Intelligence in Surgery - Future of Surgery

 

I agree with Dr. Mohr in as much as I truly believe the future of surgery, just as the future of medicine means a close cooperation between humans and medical technology. I also cannot stress enough times that robots and other products of the rapid technological development will not replace humans. The two will complement each other’s work in such a successful way that we had never seen nor dreamed about before. But only if we learn how. [The Medical Futurist]

January 18, 2017 / by / in , , , , , , , , ,
Stem Cells Are Poised to Change Health and Medicine Forever


Image: Shutterstock.

 

We are at the cusp of a stem cell revolution.

 

Understanding and harnessing these unique cells may unlock breakthroughs in longevity and therapeutic solutions to all kinds of chronic diseases and regenerative opportunities.

Last month, I took a trip down to the Stem Cell Institute in Panama City with Dr. Bob Hariri (co-Founder of Human Longevity Inc.) to get stem cell injections in my knee and shoulder as an alternative to reconstructive surgery.

Aside from the injections, I had a chance to interview the directors of the institute, Dr. Jorge Paz Rodriguez and Dr. Neil Riordan, as well as Dr. Bob Hariri, to discuss the future of stem cell therapy.

In this post we will discuss:

  1. What are stem cells?
  2. Future of stem cell therapeutics
  3. Recent success stories with stem cells

What Are Stem Cells?

Stem cells are undifferentiated cells that can transform into specialized cells such as heart, neurons, liver, lung, skin and so on and can also divide to produce more stem cells.

In a child or young adult, these stem cells are in large supply, acting as a built-in repair system.

They are often summoned to the site of damage or inflammation to repair and restore normal function.

But as we age, our supply of stem cells begins to diminish as much as 100- to 10,000-fold in different tissues and organs.

In addition, stem cells undergo genetic mutations, which reduce their quality and effectiveness at renovating and repairing your body.

A useful analogy is to imagine your stem cells as a team of repairmen in your newly constructed mansion.

When the mansion is new and the repairmen are young, they can fix everything perfectly. But as the repairman age and reduce in number, your mansion eventually goes into disrepair and eventually crumbles.

But what if you could restore and rejuvenate your stem cell population?

One option is to extract and concentrate your own autologous adult stem cells from places like your adipose (or fat) tissue. But these stem cells are fewer in number and have undergone mutations from their original ‘software code.’

Many scientists and physicians now prefer an alternative source, obtaining stem cells from the placenta or umbilical cord, the leftovers of birth.

These stem cells, available in large supply and expressing the undamaged software of a newborn, can be injected into joints or administered intravenously to rejuvenate and revitalize.

One can think of these stem cells as chemical factories generating vital growth factors that can help to reduce inflammation, fight autoimmune disease, increase muscle mass, repair joints, and even revitalize skin and grow hair.

Future of Stem Cell Therapeutics

Over the last decade, the number of publications per year on stem cell-related research has increased 40x. The stem cell market is expected to reach $170 billion by 2020.

Rising R&D initiatives to develop therapeutic options for chronic diseases and growing demand for a regenerative treatment option are the most significant drivers of this budding industry.

Here are the top four areas in the space to watch:

1. Tissue engineering: Tissue engineering using the body’s own stem cells to repair, replace or augment diseased tissue is a rapidly evolving field. Patients with a variety of diseases may be treated with transplanted tissues and organs. However, we face a shortage of donor tissues and organs, which is worsening yearly because of the aging population. Scientists in the field of tissue engineering are applying the principles of cell transplantation, material science, and bioengineering to construct biological substitutes that will restore and maintain normal function in diseased and injured tissues. The stem cell field is also advancing rapidly, opening new options for cellular therapy and tissue engineering. Use of postnatal stem cells has the potential to significantly alter the perspective of tissue engineering.

2. Stem cell banking: “At your moment of birth, you are probably at the point of biological perfection,” says Dr. Bob Hariri. “Your system hasn’t been exposed to all of those injurious stimuli, like electromagnetic radiation, chemicals, etc., and your biological software is uncorrupted.” Stem cell banking allows us to capture stem cells with your original, uncorrupted DNA at birth, replicate them into a large number of future dosages and then freeze those doses. Hariri discovered that in addition to cord blood (the blood found in the umbilical cord of a newborn), the placenta of a newborn is an organ very rich in stem cells. Rather than discard the leftovers of birth, placentas, if saved, may hold the key to a longer and healthier life. Hariri created a business called LifebankUSA, which provides private cell banking (FYI, this is where we banked our children’s stem cells). Lifebank isolates, processes and cryopreserves cells (putting them into a deep freeze, about minus 180 degrees Celsius), keeping them in suspended animation at the most pristine state of their existence.

3. Clinical applications of MSCs: Mesenchymal stem cells, the major stem cells for cell therapy, have been used in the clinic for approximately 10 years. Currently, 344 registered clinical trials in different clinical trial phases are aimed at evaluating the potential of MSC-based cell therapy worldwide. From animal models to clinical trials, MSCs have afforded promise in the treatment of numerous diseases. The ability of MSCs to differentiate into osteoblasts, tenocytes and chondrocytes has attracted interest for their use in orthopedic settings. First, MSCs have been shown to be beneficial in treating bone disorders, such as osteogenesis imperfecta (OI) and hypophosphatasia. Other promising therapeutic avenues for MSCs include the treatment of autoimmune disease, cardiovascular disease, liver disease and cancer.

4. Parabiosis: A San Francisco-based startup called Ambrosia recently commenced one of the trials on parabiosis. Their protocol is simple: Healthy participants aged 35 and older get a transfusion of blood plasma from donors under 25, and researchers monitor their blood over the next two years for molecular indicators of health and aging. The study is patient-funded; participants, who range in age from late 30s through 80s, must pay $8,000 to take part, and live in or travel to Monterey for treatments and follow-up assessments. Ambrosia’s founder Jesse Karmazin became interested in launching a company around parabiosis after seeing impressive data from animals and studies conducted abroad in humans: In one trial after another, subjects experience a reversal of aging symptoms across every major organ system. “The effects seem to be almost permanent,” he says. “It’s almost like there’s a resetting of gene expression.” This company has recently received funding from Peter Thiel. Infusing your own cord blood stem cells as you age may have tremendous longevity benefits.

Recent Stem Cell Success Stories

Below are my top three stories demonstrating the incredible research and implications for stem cells over the past 12 months:

a) Stem Cells Able to Grow New Human Eyes: Biologists led by Kohji Nishida at Osaka University in Japan have discovered a new way to nurture and grow the tissues that make up the human eyeball. The scientists are able to grow retinas, corneas, the eye’s lens, and more using only a small sample of adult skin.

b) Stem Cell Injections Help Stroke Victims Walk Again: In a study out of Stanford, of 18 stroke victims who agreed to stem cells treatments, seven of them showed remarkable motor function improvements. This treatment could work for other neurodegenerative conditions such as Alzheimer’s disease, Parkinson’s and Lou Gehrig’s Disease.

c) Stem Cells Help Paralyzed Victim Gain Use of Arms: Doctors from the USC Neurorestoration Center and Keck Medicine of USC injected stem cells into the damaged cervical spine of a recently paralyzed 21-year-old man. Three months later, he showed dramatic improvement in sensation and movement of both arms.

In Conclusion

As humans, we’ve just come to accept the notion that we are going to die.

However, the keys to our longevity and health may lie in our source code.

In the next two decades, stem cells are going to change medicine forever, extend life, and potentially save your life.

We truly live during the most exciting time ever in human history.

[SingularityHub]

January 18, 2017 / by / in , , , , , , , ,
Algorithm Predicts What Happens Next in a Photo and Makes It Into a Video

Image Credit: MIT

 

Imagine if your favorite picture could automatically be converted into a short video and labeled. Sound like a fantasy? Maybe not for much longer.

Using a deep learning algorithm, MIT’s Carl Vondrick, Hamed Pirsiavash, and Antonio Torralba recently generated one second of predictive video based on a single still frame.

Called Scene Dynamics, the software has been taught with roughly two million unlabeled videos. After being fed a new image, the system runs two competing neural networks. The first generates the predictive video while the second discerns if the videos are real or fake. Beyond predicting an impressive number of frames based on assumed motion, the algorithm also classifies the specific action occurring. While clearly not perfect, the results are impressive already.

 

 

It’s notable the software learned from unlabeled videos. Deep learning programs are usually fed masses of meticulously labeled data (images, for example). This takes a lot of time and effort and limits learning to tailored experiences. The researchers hope their work will advance less laborious “unsupervised learning,” reducing the need for special data sets and allowing machines to learn from messier information.

Also, this isn’t the only project with the goal of predictive video.

Visual Dynamics is a similar project (also out of MIT) working to generate new frames of predictive video per source frame. The difference? Visual Dynamics predicts short snippets of what may theoretically happen next, while Scene Dynamics creates entirely new longer sequences of video that didn’t exist before. Also, Scene Dynamics can separate background from subjects and generate new content for each.

Predictive video from stills has a variety of immediate applications, most notably creating video “out of thin air.” And there might even be room for more creative endeavors down the road.

“I sort of fantasize about a machine creating a short movie or TV show,” lead author Carl Vondrick told Motherboard. “We’re generating just one second of video, but as we start scaling up maybe it can generate a few minutes of video where it actually tells a coherent story. We’re not near being able to do that, but I think we’re taking a first step.”

Beyond video creation, similar motion prediction capabilities might be integrated into computer vision systems, allowing robots to better guess how people and objects in front of them will move. Such powers might help them avoid damaging themselves or hurting others around them.

More speculatively, if software like this can predict motion, what else might it be trained to predict?

One possible use in the future could be predicting what blurry or distorted pixels in videos should look like if sharpened. Low-resolution, compressed, or artifact-laden video would then be automatically upgraded to high resolution.

According to the researchers, they also see use-cases for improved security tactics and self-driving technology. But the dark side of multimedia manipulation is clear too. We may eventually see it power propaganda or generate falsified evidence (assuming fakeness can’t be easily detected).

Thankfully, we still have quite a way to go before this concern is valid. But for better or worse, as media manipulation becomes more flexible and widespread, video as a medium will shift into something more fluid than static. Ultimately, how such technology is used will depend on the motivation of each user.

The code is already available on GitHub if anyone wants to start playing around today. And the original video data set is also available on the Scene Dynamics website. [SingularityHub]


 

January 18, 2017 / by / in , , , , , , , , ,
When the Worst Happens, These Amazing Robots Will Come to the Rescue

 

The attacks of September 11, 2001, will go down in American history for many reasons—the deaths of nearly 3,000 people chief among them.

A footnote in that particular history book is of interest to us here: 9/11 was the first time robots were used in a real search and rescue effort in the United States. That bit of unofficial history comes from Robin Murphy, director of the Center for Robot-Assisted Search and Rescue (CRASAR) at Texas A&M University, and a leading expert in the field.

In the 15 years since then, roboticists have designed all manner of machines to help mobilize rescue efforts or map disaster areas. There are small robots that can jump high and biobots—bug cyborgs—that can scurry through rubble. Some are humanoid-shaped, while others resemble small Mars rovers. A handful have been deployed into real-life scenarios, while many are still under development.

In the book Robotics for Future Presidents, Murphy emphasizes the role that robotics researchers play in disaster response: “Me and my colleagues are researchers in robotics, not disaster responders. Our job is to empower the responders with rescue robots that are easy to use and effective. Rescue robots don’t replace people or dogs. They go to places where people or dogs can’t go and assist responders in innovative ways.”

Debugging a disaster

One of the more recent innovations involves not strictly robots but cyborgs—and not of the two-legged variety.

Researchers at North Carolina State University have created insect cyborgs they can control remotely. Now they are betting the bugs will prove to be valuable cartographers with the assistance of an unmanned aerial vehicle or UAV.

Photo by Alper Bozkurt

“The idea would be to release a swarm of sensor-equipped biobots—such as remotely controlled cockroaches—into a collapsed building or other dangerous, unmapped area,” says Edgar Lobaton, an assistant professor of electrical and computer engineering at NC State, in a press release about two papers describing the work.

The technology developed by Lobaton and colleagues would allow the biobots to move freely within range of a beacon carried aboard a UAV. Radio signals from the biobots are fed into a program that translates the sensor data from their movements into a map of the environment in which the bugs were released.

Lobaton’s work focused on the development of algorithms for mapping using multiple biobots. He says by email that one of the biggest challenges is that typical strategies for determining position, such as GPS or visual sensors, are not well-suited for the biobot swarm.

“This is why we had to develop a new methodology that only depends on weak localization information between the agents,” he says, referring to the insect cyborgs. “In particular, we only use encounter information between them whenever they get within a specific range of each other. This led to the development of a new framework to manage this type of scenario.”

The article on the framework for developing local maps and stitching them together was published in Robotics and Autonomous Systems. A second article on the theory of mapping based on mobile sensors’ proximity to each other was published in IEEE Transactions on Signal and Information Processing over Networks.

Jumping over disaster

Duncan Haldane at the University California, Berkeley, developed the world’s highest-jumping untethered robot, modeled on the galago, a nocturnal primate in Africa known for its amazing vertical leap. A visit to a FEMA search and rescue training site inspired the robot, nicknamed SALTO (saltatorial locomotion on terrain obstacles), which is capable of a standing jump up to one meter.

“After seeing how challenging it would be to move rapidly across an urban disaster site, I wanted to figure out some new strategies for robots of any scale that would enable that motion,” says Haldane, whose work recently appeared in the inaugural issue of Science Robotics.


 

Biology was his guide: specialized jumpers have a “super-crouch posture, a leg configuration that allows them to stay down for longer, letting their muscles store energy in their stretchy tendons, which is later released to produce high-power jumps,” he says.

“We built a single degree for freedom leg mechanism that uses this idea—new to robotics—and showed that we can produce 2.94 times more jumping power than would have been possible without the leg mechanism,” he explains by email. “Building the leg was hard, and we actually developed new methods for designing linkages to do it.”

Walking toward disaster

Researchers from other parts of the world are developing other types of robots with search and rescue in mind.

For example, a team of Italian researchers is developing Walk-Man. It’s not a retro version of the now-obsolete portable music player, but a nearly two-meter-tall robot meant to be a full-fledged member of a SAR team.

Euronews reported that Walk-Man has joints and motions similar to a human body, with hands capable of powerful manipulations. It is reportedly fitted with a stereo vision system and a rotating 3D-laser scanner. Like Haldane, Italian scientists took some clues from nature.

“Many principles that exist in biology have given us inspiration on how [we could design] a robot,” research engineer Ioannis Sarakoglou tells Euronews, explaining that Walk-Man relies largely on gravity rather than energy to move.

Coming to the rescue

Walk-Man, biobots and Salto may represent the future of rescue robots, but the typical machines used in disaster response today are unmanned aerial, land and marine vehicles—modestly sized robots that provide vital information about places emergency responders can’t immediately reach or assess easily.

In a TEDWomen talk, Murphy says if you can reduce the response to a disaster by one day, you can reduce the overall recovery time by 1,000 days.

“Ground, aerial and marine systems are becoming commonplace for different types of disasters,” Murphy says.

 

Murphy’s teams and their robots have responded to nearly 50 disasters in a dozen countries since 9/11, including Hurricane Katrina and the Crandall Canyon Utah mine collapse. Hurricane Katrina was the first time an unmanned aerial vehicle was used in disaster response. Now UAVs are a key tool for responders needing to get a bird’s eye view of a disaster scene.

Through CRASAR at Texas A&M, Murphy also leads the volunteer search-and-rescue group Roboticists Without Borders. The organization, in part, matches professionals in the use of ground, aerial or marine robots with agencies around the world that are responding to disasters. Roboticists Without Borders covers expenses for up to 10 days for each incident.

The hope, Murphy says, is to accelerate the adoption and improve the use of robots in disasters through RWB. The goal would be to put Roboticists Without Borders out of business by 2025, she adds.

“Robots can make a disaster go away faster,” Murphy says. “Look for the robots, because robots are coming to the rescue.” [SingularityHub]

January 18, 2017 / by / in , , , , , , ,
A Quick Guide to Enterprise App Marketing

 

Whether you’re creating a web app or a mobile app, there’s plenty of room in the B2B space for apps that solve the problems of business owners and managers.

In some respects, creating an enterprise application is a better model. Your customers are willing to spend money to simplify their process and save time, and they have revenue coming in the door to pay for your product.

But once you’ve built your product (or at least an early version of it), how do you market it? How do you put it in the hands of the right people?

B2B marketing is actually simple. Not easy, but simple. It requires constant product and customer development, creating supporting content, and targeting the right people.

Let’s dive in!

Continue iterating

No amount of marketing will make a poor product successful. Similarly, great products market themselves.

Jordan Stolper, CEO of StoryDesk, tells DMN: “The greatest misconception of app development is that once the software is built, the development ends.”

His point is that software should be continuously refined. You’re bound to make some mistakes. You need to monitor your analytics and speak with your customers to find ways to improve the application. What could be better? What should be removed? What new features should be added?

There are a million ways to iterate on your product. You probably have a million ideas on how to improve the product already. It’s not hard to come up insights. The trick is to prioritize your development (and avoid overdevelopment).

Alex Adamopoulos, founder and CEO of Emergn, believes that “one of the biggest differentiators between companies that thrive and those that fail is the ability to prioritize effectively.” (His article explains nine prioritization techniques, so check it out.)

This is important to keep in mind because many application owners fail to budget for ongoing development. They count their pennies right up until the app is published and wait for results.

Great products are shared organically. If your application is useful and performs well, your B2B customers will spread word of your tool throughout their industry in the spirit of making their friends and colleagues lives easier.

 

Focus on customer success

Your customers are looking for a solution to a problem. If they don’t realize value with your product (even due to their poor use), they’ll look elsewhere. And you can’t grow if you can’t retain your current customers.

Customer success is the practice of helping your customers find that value. Like product iteration, it helps you create a better application that markets itself. This is critical if you sell a monthly subscription SaaS.

This visual from For Entrepreneurs shows how happy customers send more leads into your sales pipeline. These leads are warmer and move through your sales process faster than typical leads.
 

 

The goal of a customer success manager is to onboard your users (not in a technical sense, but in a moment of first value sense) and make sure the product is continually serving their goals. Over time, this doesn’t just make the customer like your product – it makes them dependent on your product.

“Sales are important, but they shouldn’t be your focus when you need your current customers to pay you next month and every month thereafter,” says customer success consultant Nils Vinje. “Sales only begin the relationship. Customer success maintains the relationship for the long haul.”

 

Content, content, content

Content is one of the most effective ways to generate leads. Content on your website stays around forever, drawing traffic and either sending visitors to your sales pages or converting them to email subscribers (who are later sold on the product).

Content is especially useful in a B2B climate because people are constantly looking for solutions to make their jobs easier, complete difficult tasks, get more done in less time, and build automation into their process.

Ideally, your content should be the beginning of a marketing funnel that flows like this:

  • Content collects traffic.
  • Traffic joins your email list (now they are leads).
  • Leads are nurtured with additional content (perhaps a drip campaign that solves a particular problem or regular blog posts) over time.
  • Leads are targeted for sales.

For best results, segment your list as best you can based on characteristics that matter to your business, such as industry, company size, workflow, current solution, revenue, etc.

For instance, you might find that there are two types of people within your customers’ organizations who approach you: developers and project managers. A person who signed up in a blog post about high-level project planning would be tagged as “project manager.” You could send them targeted content and links to landing pages and sales pages that are relevant to their job.

If you want to see some great examples of content marketing, check out this article: 4 Apps Nailing Content Marketing (And How You Can Too)

 

Make a few videos

According to Google, 70% of B2B product buyers watch videos throughout the purchase journey. That claim and more are backed up in Tubular Insights’ 2015 B2B Video Content Marketing Survey:

  • 96% of B2B organizations create video content
  • 73% say video has positively impacted their marketing results
  • 41% plan to increase spending on video marketing in 2015

It’s also worth noting that Google’s search algorithm favors video content. Websites with videos see a 40% increase in traffic to pages with videos.

B2B marketing agency KoMarketing explains the value of video content well: “Video brings an immediacy, digestibility, context and personality that even the most clever of text-based business content struggles to achieve… at least in our instant gratification, device-ruled world.”

A great video should tell a story. It should be intriguing, but informative (remember, you aren’t entertaining). It uses a logical flow that starts by acknowledging the visitor’s problem, positioning the product as a solution and then compels the viewer to take action.

Most importantly, a video should feel genuine. The viewer should feel like you want to partner with them to solve the problem, not just transfer money from their pocket to yours.

 

Prospect hunting

Depending on your niche, mass marketing techniques might not be effective. If you’re selling a scheduling tool for dentist offices (but only ones large enough to afford it), you don’t have time for content or word-of-mouth to spread.

You have to get on the phone and sell. (Well, maybe by email.)

But first, you need a list of prospects who fit your ideal customer profile. (If you haven’t built a customer profile, use this link.)

First, start with social media. With 400 million members, LinkedIn has a tremendous pool of leads. 80.3% of all B2B leads generated through social media came from the social platform.

LinkedIn’s advanced search and Sales Navigator are excellent tools to find and approach people. Send personalized messaging that doesn’t sound like a template. Speak about benefits, not features. Wait a few days, then follow up.

You should also dive into some LinkedIn groups that relate to your business and industry. Engage with people regularly, but don’t be salesy. When you spot someone you can help, target them for selling.

After exhausting LinkedIn, try a lead finding tool like any one of these:

Finally, browse Quora for questions that relate to the problem you solve (not your product). When someone asks a question, you can swoop in and answer it, then reach out for a sale.

Use this list of B2B marketing tactics to start marketing right away.

Final thoughts

Here’s one final piece of advice: Listen to your customers. You need to know the precise problems they deal with every day and where they are searching for those solutions.

Speak to the people who are already paying for your product. Learn as much as you can from them. How do they prefer to use your product? Which features are necessary? What would make their lives easier? How do previous solutions compare?

Once you know what you customers (and potential customers) need and prefer, your marketing strategy will clarify. [Koombea]

January 17, 2017 / by / in , , , , ,
A Raspberry Pi-Powered, Alexa-Controlled Mirror

You’ve probably seen rumblings of ‘smart mirrors’ being vaguely available for sale in the future or to build now. If you’d like step-by-step instructions to make your own, look no further than Ben Eagan’s latest project.

 

 

According to his summary, it simply requires constructing a frame around a monitor, creating a two-way mirror, and setting up MagicMirror software on a Raspberry Pi.

Besides displaying information visually, Eagan added voice interaction to the mirror by installing Alexa software on his RPi. Now it can finally answer questions like, “How many kilometers to the sun,” or perhaps, “Who is the fairest of them all?”

Sound like a smart accessory you need in your bedroom or living room? Check out Eagan’s blog post to get started.

[Hackster.io]

January 17, 2017 / by / in , , , , ,
Future of App Development – Native Apps or Web App?

progressive web app

 

Today all digital businesses is moving towards native mobile apps. Most of the companies are creating their platforms which are app only. And they have significant reasons for having app only platform over web based platforms:

Reasons Why Mobile Apps Have Become So Popular

1) Increased User Interest

When you develop an app, it gives you an easy way to showcase your products or services to your customers and prospective customers. Whenever they want, they can just use it as a one-stop point to get all the info they need.

2) Enhanced Engagement

Most shoppers cannot resist the temptation of a good deal or a great discount, especially when one stares at their face. And this is exactly what you can do with your mobile app.

3) Real Time Push Promotions

Suppose you have an apparel and accessories boutique at a central location. And you know that many prospective customers walk by your store every day. What if you design an app that lures them to your store when they are in the vicinity?

4) Quicker Support

While it is often a hassle to receive and respond to a customer support request, the same becomes easy when you have an appropriate app to do it. With a mobile app that can offer instructions and how-to’s, you are sure to win approval.

5) Ease of Use

Users today wish for a fuss-free experience, whether they access your site or your app, and whether they do it from their PC or their Smartphone. With a good plan and a clear vision, it becomes possible to deliver on their expectations.

6) Regular Usage & Personalization

If your target users are going to be using your app in a personalized fashion on a regular basis (think EverNote) then an app provides a great way to do that.

7) Native Functionality or Processing Required

Mobile web browsers are getting increasingly good at accessing certain mobile-specific functions such as click-to-call, SMS and GPS. However, if you need to access a user’s camera or processing power an app will still do that much more effectively.

8) No Connection Required

If you need to provide offline access to content or perform functions without a network/wireless connection then an app makes sense.

All the reasons look significant, and I must say they are proving their worth in the market, but one thing which makes all these things still useless is, you have to make customers download your app, which is the most challenging thing to do.

And I have seen most of the companies doing anything to make sure that their app is downloaded by their target user. They are giving huge discounts, doing a lot of advertisements, but I think you can’t force users to download a different app for each and every service they want.

 

Issues with apps

1) As I have mentioned, you have to make users to download your app, and that is not easy at all.

2) All mobile devices have limitations: memory, performance etc.

We need to take care of different mobile devices while developing an app which is a huge challenge for app developers to give same user experience on different mobile devices.

Similar Read:  What Can We Expect from FinTech Sector in 2017?

The devices can have different platforms on which they are working, different specifications, different screen sizes etc.

3) If users have so many apps then your app will be lost in the pool of other apps.

 

How web apps will give all the features of a native app with the the simplicity of website?

This is a big and difficult question for web developers.

Let’s discuss first what are the benefits of having a web app then will try to find how they can be improved or how they are improving:

1) Immediacy — Mobile Websites Are Instantly Available

A mobile website is instantly accessible to users via a browser across a range of devices (iPhone, Android, BlackBerry, etc). Apps on the other hand require the user to first download and install the app from an app marketplace before the content or application can be viewed — a significant barrier between initial engagement and action/conversion.

2) Compatibility — Mobile Websites are Compatible Across Devices

A single mobile website can reach users across many different types of mobile devices, whereas native apps require a separate version to be developed for each type of device. Furthermore, mobile website URLs are easily integrated within other mobile technologies such as SMS, QR Codes and near field communication (NFC).

3) Upgradability — Mobile Websites Can Be Updated Instantly

A mobile website is much more dynamic than an app in terms of pure flexibility to update content. If you want to change the design or content of a mobile website you simply publish the edit once and the changes are immediately visible; updating an app on the other hand requires the updates to be pushed to users, which then must be downloaded in order to update the app on each type of device.

4) Findability — Mobile Websites Can be Found Easily

Mobile websites are much easier for users to find because their pages can be displayed in search results and listed in industry-specific directories, making it easy for qualified visitors to find you. Most importantly, visitors to your regular website can be automatically sent to your mobile site when they are on a handheld (using device-detection). In contrast, the visibility of apps are largely restricted to manufacturer app stores.

5) Shareability — Mobile Websites Can be Shared Easily by Publishers, and Between Users

Mobile website URLs are easily shared between users via a simple link (e.g. within an email or text message, Facebook or Twitter post). Publishers can easily direct users to a mobile website from a blog or website, or even in print. An app simply cannot be shared in this fashion.

6) Reach — Mobile Websites Have Broader Reach

Because a mobile website is accessible across platforms and can be easily shared among users, as well as search engines, it has far greater reach capability than a native app.

7) LifeCycle — Mobile Websites Can’t Be Deleted

The average shelf-life of an app is pretty short, less than 30 days according to some research, so unless your app is something truly unique and/or useful (ideally, both), it’s questionable how long it will last on a user’s device. Mobile websites on the other hand are always available for users to return to them.

Similar Read:  Simple Guide to Create DIY Internet Marketing Strategy
8) A Mobile Website Can be an App

Just like a standard website, mobile websites can be developed as database-driven web applications that act very much like native apps. A mobile web application can be a practical alternative to native app development.

9) Support and Sustainability

The investment considerations of app vs website don’t end with the initial launch; properly supporting and developing an app (upgrades, testing, compatibility issues and ongoing development) is more much more expensive and involved than supporting a website over time.
So we have some answers for this , which are still looks like a hypothesis.

 

Now how to compete with native apps

Some recent innovations in the field of web app development:

1) Push Notifications for web interface

Push notification plays a vital role in advertisement, enhances the user engagement, and many other things.

2) Geo fencing on web

Today all the apps are personalised for you. They work according to your taste, your location etc.

So, for web to work like these we need Geo Fencing for Web.

3) Off-line Support for some features

Apps provide offline features, like Facebook allows you to update your status even when you are not connected to web, and when you are back in network they will update your status automatically.

So for all these things many web based companies are working and have launched new technologies to support all these features of a native app on web apps, even they have released beta versions of some of the features.

For Example:

1) Google’s material design on websites, we have Polymer which is still in early stage and not that many developers are familiar with it yet. But yes I guess in future developer community will use this platform or some other coming platforms to give web development a new face.

2) Bootstrap: Helping developers in making mobile friendly websites.

3) Service Builder, which will provide offline support for web apps.

4) Push Notification and Geo Fencing in latest version of Google Chrome for developers and in Mozilla Firefox.

And many more…

 

In Conclusion

As long as mobile remains a relatively new frontier, the “app vs web” question will remain a very real consideration for organizations seeking to establish a mobile presence. If your mobile goals are primarily marketing-driven, or if your aim is to deliver content and establish a broad mobile presence that can be easily shared between users and found on search engines, then the a mobile website is the logical choice. On the other hand, if your goal is interactive engagement with users, or to provide an application that needs to work more like a computer program than a website, then an app is probably going to be required.

Want to share some websites which are working on all these futuristic designs and technologies.

https://poly-mail.appspot.com/
http://foodtrack.de/
https://www.chromestatus.com/features/5047308127305728
http://1.daily-stock-forecast.appspot.com/favorite/
http://pubnub.github.io/paper-chat/
https://home-assistant.io/demo/

[iamwire]

January 17, 2017 / by / in , , , , ,
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